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human liver tumor derived cell lines snu387  (ATCC)
96
ATCC human liver tumor derived cell lines snu387
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Human Liver Tumor Derived Cell Lines Snu387, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human liver tumor derived cell lines snu387 - by Bioz Stars, 2026-04
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cancer cell line  (ATCC)
97
ATCC cancer cell line
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Cancer Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cancer cell line/product/ATCC
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cancer cell line - by Bioz Stars, 2026-04
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liver hepg2 cancer cell lines  (ATCC)
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ATCC liver hepg2 cancer cell lines
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Liver Hepg2 Cancer Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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liver hepg2 cancer cell lines - by Bioz Stars, 2026-04
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whole mouse livers  (Miltenyi Biotec)
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Miltenyi Biotec whole mouse livers
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Whole Mouse Livers, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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whole mouse livers - by Bioz Stars, 2026-04
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hepg2 liver cancer tumor growth  (ATCC)
99
ATCC hepg2 liver cancer tumor growth
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Hepg2 Liver Cancer Tumor Growth, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hepg2 liver cancer tumor growth - by Bioz Stars, 2026-04
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n1s1 liver tumors  (Dawley Inc)
90
Dawley Inc n1s1 liver tumors
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
N1s1 Liver Tumors, supplied by Dawley Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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liver, islet, tumor cell culture  (Insphero Inc)
90
Insphero Inc liver, islet, tumor cell culture
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Liver, Islet, Tumor Cell Culture, supplied by Insphero Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/liver, islet, tumor cell culture/product/Insphero Inc
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liver, islet, tumor cell culture - by Bioz Stars, 2026-04
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dosimetric guidelines for sbrt of primary liver tumors  (Hytec Inc)
90
Hytec Inc dosimetric guidelines for sbrt of primary liver tumors
FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and <t>SNU387)</t> by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.
Dosimetric Guidelines For Sbrt Of Primary Liver Tumors, supplied by Hytec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/dosimetric guidelines for sbrt of primary liver tumors/product/Hytec Inc
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FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.

Journal: Journal of Cancer

Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10

doi: 10.7150/jca.125659

Figure Lengend Snippet: FAM188B expression is upregulated and associated with poor prognosis in hepatocellular carcinoma (HCC). (A) Expression of FAM188B mRNA in tumor and non-tumor tissues and its association with cancer stage and tumor grade in UALCAN database. (B) The expression of FAM188B protein was evaluated in normal hepatocytes (LX-2) and in hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (C) Validation of FAM188B expression after overexpression in the indicated cell lines using western blotting (n = 3). (D) Proliferation of MHCC97H and Huh7 cells, as detected by performing CCK-8 assays (n = 10). (E) Migratory and invasive capacities of MHCC97H and Huh7 cells within 24 hours, as evaluated using Transwell assays (scale bar, 50 μm) (n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns, not significant. The data are expressed as the mean ± SD of three independent experiments.

Article Snippet: Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.

Techniques: Expressing, Western Blot, Biomarker Discovery, Over Expression, CCK-8 Assay

FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.

Journal: Journal of Cancer

Article Title: FAM188B promotes progression of hepatocellular carcinoma by regulating YAP/TAZ via interaction with USP10

doi: 10.7150/jca.125659

Figure Lengend Snippet: FAM188B interacts with USP10. (A) Schematic illustration of IP and GO enrichment of identified proteins (using all proteins in the species database as the background). Fisher's exact test was used to analyze the significance and P value < 0.05 were considered significant. (B) Expression levels of USP10 mRNA in tumor (n = 374) and non-tumor (n = 50) tissues and its relationship with FAM188B, based on a public database. (C) The protein expression level of USP10 was evaluated in normal hepatocytes (LX-2) and hepatocellular carcinoma (HCC) cells (MHCC97H, Huh7, Hep3B and SNU387) by western blot. (D) Localization of USP10 in HCC cells (scale bar, 20 μm). (E) Co-IP assays to confirm the protein-protein interaction between FAM188B and USP10 in vitro . **p < 0.01, ***p < 0.001. The data are expressed as the mean ± SD of three independent experiments. IP, immunoprecipitation. Co-IP, co-immunoprecipitation.

Article Snippet: Human liver tumor-derived cell lines SNU387 and Hep3B, human embryonic kidney HEK293T cells were obtained from the American Type Culture Collection (Manassas, VA, USA) in 2021.

Techniques: Expressing, Western Blot, Co-Immunoprecipitation Assay, In Vitro, Immunoprecipitation